Fort Assumption was a French fortification constructed in 1739 on the fourth Chickasaw Bluff on the Mississippi River by Jean-Baptiste Le Moyne, Sieur de Bienville's French army.
The fort was used as a base against the Chickasaw in the abortive Campaign of 1739.
Later French explorers led by René-Robert Cavelier, Sieur de La Salle likely encountered the Chickasaw.
The European-American city of Memphis was not founded until 1819.
They inhabited the region of modern-day Tipton, Lauderdale and Shelby counties during the time of first contact with Europeans, at the arrival of the de Soto Expedition.